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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
22.42
Human Site:
S1369
Identified Species:
37.95
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
S1369
S
G
D
S
I
E
V
S
R
N
V
E
E
I
V
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
S1369
S
G
D
S
I
E
V
S
R
N
V
E
E
I
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
T1369
G
G
D
F
V
E
V
T
R
N
V
E
G
V
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
T1369
T
G
D
S
V
E
V
T
R
N
V
E
Q
I
V
Rat
Rattus norvegicus
NP_001101888
2143
241191
T1369
N
G
D
S
I
E
V
T
R
N
V
E
E
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
S1380
D
S
D
L
S
E
S
S
R
G
V
E
E
V
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
E1364
E
G
G
S
S
Q
S
E
G
H
M
E
T
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
P1329
G
H
N
E
L
V
I
P
V
L
K
V
F
A
D
Honey Bee
Apis mellifera
XP_393800
2028
231830
S1270
A
Y
S
I
Q
I
I
S
K
T
I
E
T
V
V
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
I945
I
F
S
N
R
V
L
I
E
R
L
A
A
Y
D
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
E930
S
A
I
F
G
S
M
E
E
D
E
L
H
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
F1272
L
L
I
L
K
D
I
F
D
S
L
N
M
N
P
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
E1064
L
V
N
F
K
I
G
E
A
R
I
L
I
E
F
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
A1083
L
L
T
S
F
V
V
A
Y
E
H
I
P
S
H
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
60
N.A.
73.3
86.6
N.A.
N.A.
53.3
N.A.
26.6
N.A.
0
20
0
6.6
P-Site Similarity:
100
100
N.A.
80
N.A.
100
100
N.A.
N.A.
60
N.A.
53.3
N.A.
20
53.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
8
0
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
43
0
0
8
0
0
8
8
0
0
0
0
15
% D
% Glu:
8
0
0
8
0
43
0
22
15
8
8
58
29
8
0
% E
% Phe:
0
8
0
22
8
0
0
8
0
0
0
0
8
0
8
% F
% Gly:
15
43
8
0
8
0
8
0
8
8
0
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
8
8
0
8
0
8
% H
% Ile:
8
0
15
8
22
15
22
8
0
0
15
8
8
29
0
% I
% Lys:
0
0
0
0
15
0
0
0
8
0
8
0
0
0
0
% K
% Leu:
22
15
0
15
8
0
8
0
0
8
15
15
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
8
0
0
% M
% Asn:
8
0
15
8
0
0
0
0
0
36
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
43
15
0
0
0
0
0
% R
% Ser:
22
8
15
43
15
8
15
29
0
8
0
0
0
15
0
% S
% Thr:
8
0
8
0
0
0
0
22
0
8
0
0
15
0
0
% T
% Val:
0
8
0
0
15
22
43
0
8
0
43
8
0
29
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _